![]() ![]() ![]() Do not mix with other medicinal products.Prior to use, unopened vials may be kept at room temperature (25C or 77F) for up to 48 hours if stored in the original package, or up to 6 hours if exposed to light.Refrigerate at 2C to 8C (36F to 46F) do not freeze.Administration should begin promptly or within 1 hour after solution has been removed from the vial.Administer as a bolus injection by injecting both vials consecutively one after another via syringe or as two consecutive infusions.Safety and efficacy have not been established in patients younger than 18 years.Ĭonsult WARNINGS section for additional precautions. No adjustment recommended Liver Dose Adjustments Continued approval may be contingent upon the results of an ongoing cohort case series study. This indication is approved under accelerated approval. Use: Reversal of the anticoagulant effects of dabigatran in patients requiring emergency surgery/urgent procedures or in the event of life-threatening or uncontrolled bleeding. Dabigatran can be initiated 24 hours after administration of this drug. Resume anticoagulant therapy as soon as medically appropriate.There is limited data to support administration of an additional 5 g.Usual Adult Dose for Reversal of Anticoagulationĥ g IV provided as two separate vials each containing 2.5 g/50 mL administer as a bolus injection by injecting both vials consecutively one after another via syringe or as two consecutive infusions. ![]()
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